Ventral tegmental (A10) system: neurobiology. 1. Anatomy and connectivity

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Neurochemistry and anatomy of the ventral medulla

The relationship between the anatomy and neurochemistry of neurons in the ventral medulla oblongata in regions that is responsible for cardiovascular, airways, and respiratory regulation was investigated. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM) were made throughout the ventral medulla in anesthetized rats. Arterial blood pressure, sympathetic nerve activity and phreni...

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Neurochemistry and anatomy of the ventral medulla

The relationship between the anatomy and neurochemistry of neurons in the ventral medulla oblongata in regions that is responsible for cardiovascular, airways, and respiratory regulation was investigated. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM) were made throughout the ventral medulla in anesthetized rats. Arterial blood pressure, sympathetic nerve activity and phreni...

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Functional connectivity of substantia nigra and ventral tegmental area: maturation during adolescence and effects of ADHD.

Dopaminergic (DArgic) pathways play crucial roles in brain function and their disruption is implicated in various neuropsychiatric diseases. Here, we demonstrate in 402 healthy children/adolescents (12 ± 3 years) and 704 healthy young adults (23 ± 5 years) that the functional connectivity of DA pathways matures significantly from childhood to adulthood and is different for healthy children and ...

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Differences in neural connectivity between the substantia nigra and ventral tegmental area in the human brain

OBJECTIVES Many animal and a few human studies have reported on the neural connectivity of the substantia nigra (SN) and the ventral tegmental area (VTA). However, it has not been clearly elucidated so far. We attempted to investigate any differences in neural connectivity of the SN/VTA in the human brain, using diffusion tensor imaging (DTI). METHODS Sixty-three healthy subjects were recruit...

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Intrinsic connectivity between the hippocampus, nucleus accumbens, and ventral tegmental area in humans.

Recent studies suggest that memory formation in the hippocampus is modulated by the motivational significance of events, allowing past experience to adaptively guide behavior. The effects of motivation on memory are thought to depend on interactions between the hippocampus, the ventral tegmental area (VTA), and the nucleus accumbens (NAcc). Indeed, animal studies reveal anatomical pathways for ...

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ژورنال

عنوان ژورنال: Brain Research Reviews

سال: 1987

ISSN: 0165-0173

DOI: 10.1016/0165-0173(87)90011-7